Cells respond to external stimuli and adapt to prolonged exposure to persistent signals to maintain cellular homeostasis. There are a number of regulatory mechanisms to achieve signal adaptation, among them are negative feedback (NFB) and incoherent feed-forward (FFS) mechanisms. We have deterministically and stochastically studied these two mechanisms in terms of their capacity for producing complex dynamics such as oscillation and multiple steady states as well as how they process intrinsic noise and noisy input signals.
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Hi, great poster. What did you use to run numerical simulations?
Thank you! I ran the simulations using Gillespie algorithm in Matlab (Matrix Laboratory), a programming language used for numerical computing.
Thank you! I ran the simulations using Gillespie’s algorithm in Matlab (Matrix Laboratory), a programming language used for numerical computing.